产品货号：
Z33666
中文名称：
SCIMP Purified抗体
英文名称：
Anti-SCIMP Purified Antibody (Clone#NVL-07)
产品规格：
0.1mg(C100)
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-SCIMP Purified Antibody (Clone#NVL-07) |
| 指标别名 | NVL |
| 克隆性 | Monoclonal |
| 检验物种 | human |
| 应用范围 | FCM,IP,WB,ICC |
| 基因名称 | SCIMP |
| 克隆号 | NVL-07 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG2a |
| 免疫原 | Recombinant intracellular part of human SCIMP.The mouse monoclonal antibody NVL-07 recognizes intracellular part of human transmembrane adaptor SCIMP.This protein of 17kDa predicted Mw migrates as a 22kDa band on SDS PAGE. |
| 计算分子量 | 17kDa |
| 成分 | Phosphate buffered saline (PBS),pH7.4,15mM sodium azide |
| 纯化方式 | Purified by protein-A affinity chromatography. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | Store at 2～8℃.Do not freeze. |
| 背景资料 | SCIMP (SLP adaptor and Csk interacting membrane protein),also known as Nvl,is a palmitoylated transmembrane adaptor protein expressed in professional antigen presenting cells,most prominently in the lymph nodes and spleen.It is associated with tetraspanin-enriched microdomains (together with MHC II).There is a close relationship between SCIMP and tyrosinkinase Lyn,which is constitutively bound to it by its SH3 domain.After MHC II-mediated stimulation in the immunological synapse SCIMP becomes phosphorylated at several tyrosine residues and provides docking sites for Grb2 and SLP65 or SLP76 adaptors transducing the signal downstream,as well as for the kinase Csk with modulatory roles. |
| Uniprot ID | Q6UWF3 |
| 基因名全称 | SLP adaptor and CSK interacting membrane protein |
| 蛋白名全称 | SLP adapter and CSK-interacting membrane protein |
| 推荐稀释比 | Flow cytometry:Intracellular staining. Western blotting:1～2μg/mL. |
相关搜索：SCIMP Purified抗体，SCIMP Purified单抗，Anti-SCIMP Purified Antibody (Clone#NVL-07)